In adolescents acne develop in

Options

A. Males in response to androgen
B. Females in response to oestrogen
C. Both males and females in response to androgen
D. both males and females in response to oestrogen

Answer

**Step-by-Step Solution:**

1. **Understanding the Question:**
- The question asks about the development of acne during adolescence and which group it primarily affects based on hormonal responses.

2. **Analyzing the Options:**
- The options provided are:
1. Males in response to androgen
2. Females in response to estrogen
3. Both males and females in response to androgen
4. Males and females in response to estrogen

3. **Identifying Key Hormones:**
- During adolescence, both males and females experience an increase in certain hormones. In males, androgens (like testosterone) are predominant, while in females, estrogen levels rise. However, both genders produce androgens.

4. **Recognizing the Role of Androgens:**
- Androgens stimulate the sebaceous (oil) glands in the skin, causing them to grow larger and produce more sebum (oil). This increased oil production can lead to acne.

5. **Evaluating the Options:**
- The first option (males only) is incorrect because acne also affects females.
- The second option (females only) is incorrect for the same reason.
- The third option (both males and females in response to androgen) is plausible since both genders experience increased androgen levels during puberty.
- The fourth option (both genders in response to estrogen) is incorrect because while estrogen is important, it is the androgens that primarily lead to acne development.

6. **Conclusion:**
- The correct answer is the third option: "both males and females in response to androgen."

**Final Answer:**
Both males and females in response to androgen.

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