Cells that display foreign antigens coupled to MHC II molecules on their surface include

Options

A. macrophages
B. dendritic cells
C. B cells
D. all of the above

Answer

To solve the question regarding which cells display foreign antigens coupled to MHC II molecules on their surface, we can follow these steps:

### Step-by-Step Solution:

1. **Understanding MHC Molecules**:
- MHC stands for Major Histocompatibility Complex. There are two main classes of MHC molecules: MHC I and MHC II.
- MHC I molecules are present on almost all nucleated cells and present antigens to CD8+ T cells.
- MHC II molecules are primarily found on specialized antigen-presenting cells (APCs) and present antigens to CD4+ T helper cells.

2. **Identifying Antigen-Presenting Cells**:
- MHC II molecules are specifically involved in displaying foreign antigens. The cells that express MHC II include:
- **Macrophages**: These are large phagocytic cells that engulf and digest pathogens and present their antigens.
- **Dendritic Cells**: These are specialized cells that capture and present antigens to T cells, playing a crucial role in initiating immune responses.
- **B Cells**: These cells can also present antigens through MHC II molecules and are involved in the humoral immune response.

3. **Analyzing the Options**:
- The question asks for cells that display foreign antigens coupled to MHC II molecules. Based on our understanding, the correct answers include:
- Macrophages
- Dendritic Cells
- B Cells

4. **Conclusion**:
- Therefore, the cells that display foreign antigens coupled to MHC II molecules on their surface include macrophages, dendritic cells, and B cells.

### Final Answer:
The cells that display foreign antigens coupled to MHC II molecules on their surface include:
- Macrophages
- Dendritic Cells
- B Cells