Administration of this substance before radiation therapy kills most of the cancer cells

Options

A. Gadolinium
B. 2-deoxyglucose
C. flouro-deoxyglucose
D. strontium sulphate

Answer

To solve the question regarding which substance, when administered before radiation therapy, kills most of the cancer cells, we can follow these steps:

### Step 1: Analyze the Options
We need to look at the given options and understand their functions and uses in relation to cancer treatment.

### Step 2: Evaluate Each Substance
1. **Gadolinium**: This substance is primarily used as a contrast agent in MRI scans to enhance image clarity. It does not have a direct role in killing cancer cells.

2. **2-Deoxyglucose**: This substance inhibits glycolysis, which is a metabolic pathway that cancer cells often rely on for energy. By stopping glycolysis, it effectively inhibits the metabolism of cancer cells, leading to their death.

3. **Fluorodeoxyglucose**: This is also used in imaging, particularly in PET scans, to visualize metabolic activity in tissues. It does not kill cancer cells.

4. **Strontium Sulfate**: This substance is used to relieve bone pain in patients with bone cancer, but it does not have a direct effect on killing cancer cells.

### Step 3: Identify the Correct Answer
From the evaluation, **2-Deoxyglucose** is the only substance that directly inhibits the metabolism of cancer cells and can kill them before radiation therapy. Therefore, the correct answer is:

**Option B: 2-Deoxyglucose**

### Summary of the Solution
The administration of **2-Deoxyglucose** before radiation therapy kills most of the cancer cells by inhibiting their glycolysis and metabolism.

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