Eukaryotic cells may differ with prokaryotic cells in having

Options

A. Locomotory structures
B. Cytoskeleton
C. Nucleus with nuclear membrane
D. All the above

Answer

To answer the question about how eukaryotic cells differ from prokaryotic cells, we will analyze the provided options step by step.

### Step-by-Step Solution:

1. **Understanding Locomotory Structures**:
- Both eukaryotic and prokaryotic cells can have locomotory structures (like flagella and cilia). However, the complexity of these structures is greater in eukaryotic cells.
- **Conclusion**: This option does not distinctly differentiate eukaryotic from prokaryotic cells.

2. **Understanding Cytoskeleton**:
- Both types of cells have cytoskeletal structures. While eukaryotic cells have a more complex and organized cytoskeleton, prokaryotic cells do have simpler forms of cytoskeletal elements.
- **Conclusion**: This option also does not provide a clear distinction between the two cell types.

3. **Understanding the Nucleus with Nuclear Membrane**:
- Eukaryotic cells possess a well-defined nucleus that is enclosed by a nuclear membrane. This nucleus contains nucleolus and is more complex.
- In contrast, prokaryotic cells do not have a true nucleus; instead, they have a nucleoid region where a single, circular piece of DNA is located.
- **Conclusion**: This option clearly differentiates eukaryotic cells from prokaryotic cells.

4. **Evaluating the Option "All of the Above"**:
- Since the first two options do not provide a clear distinction, the option "all of the above" is also incorrect.
- **Conclusion**: This option is not valid.

### Final Answer:
The correct answer is that eukaryotic cells differ from prokaryotic cells in having a **nucleus with a nuclear membrane**.