Major packaging material of chromosome is

Options

A. DNA
B. RNA
C. Histones
D. All

Answer

To answer the question regarding the major packaging material of chromosomes, we can follow these steps:

### Step-by-Step Solution:

1. **Understanding Chromosomes**:
- Chromosomes are dense, coiled structures found inside the nucleus of a cell. They play a crucial role in genetic information storage and transmission.

2. **Composition of Chromosomes**:
- Chromosomes are primarily composed of two main types of biomolecules: nucleic acids and proteins.

3. **Identifying Nucleic Acids**:
- The nucleic acids found in chromosomes are DNA (deoxyribonucleic acid) and RNA (ribonucleic acid). However, DNA is the primary component of chromosomes in most organisms.

4. **Identifying Proteins**:
- The proteins associated with chromosomes include histones and non-histones. Histones are a type of protein that helps package and organize DNA into a compact structure.

5. **Histone Proteins**:
- Histones include various types such as H1, H2A, H2B, H3, and H4. These proteins help in the winding of DNA to form nucleosomes, which further coil to form the structure of chromosomes.

6. **Conclusion**:
- The major packaging material of chromosomes is DNA. It is the DNA that carries the genetic information and is wrapped around histone proteins to form the structure of chromosomes.

### Final Answer:
The major packaging material of chromosomes is **DNA**.

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