Chromosome with two unequal arms is

Options

A. Metacentric
B. Sub-metacentric
C. Acrocentric
D. (2) and (3)

Answer

To determine the type of chromosome with two unequal arms, we need to analyze the definitions of the different types of chromosomes based on the position of their centromeres. Here's a step-by-step solution:

### Step 1: Understand Chromosome Structure
- Chromosomes consist of two arms divided by a centromere. The arms are referred to as the "p arm" (short arm) and the "q arm" (long arm).

### Step 2: Identify Types of Chromosomes
- There are different types of chromosomes based on the position of the centromere:
1. **Metacentric**: The centromere is located in the middle, resulting in two equal arms.
2. **Submetacentric**: The centromere is slightly off-center, leading to one arm being shorter (p arm) and the other being longer (q arm).
3. **Acrocentric**: The centromere is located closer to one end, resulting in a very short p arm and a longer q arm.
4. **Telocentric**: The centromere is at the very end of the chromosome, resulting in only one arm.

### Step 3: Analyze the Options
- **Metacentric**: Not the answer, as both arms are equal.
- **Submetacentric**: This is the correct answer because it has two unequal arms (one shorter and one longer).
- **Acrocentric**: While it has a very short p arm, it is not classified as having two unequal arms in the same way as submetacentric.
- **Telocentric**: This type has only one arm, so it cannot be considered as having two unequal arms.

### Conclusion
- The chromosome with two unequal arms is **Submetacentric**.