Which of the following factor/factors do not change when a catalysed reaction is compared with uncatalysed reaction

Options

A. Activation energy
B. Rate of reaction
C. Overall change in free energy
D. All the above

Answer

To solve the question regarding which factors do not change when comparing a catalyzed reaction with an uncatalyzed reaction, we can follow these steps:

### Step-by-Step Solution:

1. **Understand the Role of Catalysts**: Catalysts, such as enzymes, are substances that speed up chemical reactions without being consumed in the process. They achieve this by lowering the activation energy required for the reaction to proceed.

2. **Identify the Factors**: The factors mentioned in the question are:
- Activation energy
- Rate of reaction
- Overall change in free energy (ΔG)
- All of the above

3. **Analyze Each Factor**:
- **Activation Energy**: In a catalyzed reaction, the activation energy is lowered compared to an uncatalyzed reaction. Therefore, this factor changes.
- **Rate of Reaction**: The presence of a catalyst increases the rate of the reaction. Hence, this factor also changes.
- **Overall Change in Free Energy (ΔG)**: The overall change in free energy for a reaction is determined by the initial and final states of the reactants and products, not by the pathway taken (catalyzed or uncatalyzed). Therefore, this factor does not change.

4. **Conclusion**: The only factor that does not change when comparing a catalyzed reaction to an uncatalyzed reaction is the overall change in free energy (ΔG).

### Final Answer:
The overall change in free energy (ΔG) does not change when a catalyzed reaction is compared with an uncatalyzed reaction.

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