Archaeologists unearthed a human skull with a small dried fragment of the scalp still attached. They extracted a tiny amount of DNA from the scalp tissue. How could they obtain sufficient DNA for an analysis of the ancient man's genes?

Options

A. Use a molecular probe
B. Subjecting DNA to electrophoresis
C. Use the polymerase chain reaction
D. Subjecting DNA to restriction enzymes

Answer

To obtain sufficient DNA for analysis from the tiny amount extracted from the ancient man's scalp, the archaeologists can use the following method:

### Step-by-Step Solution:

1. **Understanding the Problem**: The archaeologists have a small fragment of scalp tissue with a tiny amount of DNA. They need a larger quantity of DNA for comprehensive analysis.

2. **Identifying the Need**: To analyze ancient genes, they require a sufficient quantity of DNA. Simply extracting the DNA from the scalp tissue is not enough.

3. **Choosing the Right Technique**: The most effective method to amplify the small amount of DNA is the Polymerase Chain Reaction (PCR). PCR is a widely used technique that allows for the amplification of DNA, producing millions to billions of copies from a small initial sample.

4. **How PCR Works**: PCR involves repeated cycles of heating and cooling, which allow the DNA to denature (separate into single strands), anneal (bind with primers), and extend (synthesize new strands). This process exponentially increases the amount of DNA.

5. **Application of PCR**: By applying PCR to the extracted DNA from the scalp tissue, the archaeologists can generate enough DNA for detailed genetic analysis, enabling them to study the ancient man's genes effectively.

6. **Conclusion**: Therefore, the best approach for the archaeologists to obtain sufficient DNA for analysis is to use the Polymerase Chain Reaction (PCR).

### Final Answer:
**Use the Polymerase Chain Reaction (PCR).**

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