Enzyme required for removing RNA primer during DNA replication is

Options

A. Primase
B. Ligase
C. DNA polymerase I
D. DNA polymerase III

Answer

To solve the question regarding the enzyme required for removing the RNA primer during DNA replication, we can follow these steps:

### Step-by-Step Solution:

1. **Understanding the Role of RNA Primers in DNA Replication**:
- During DNA replication, RNA primers are synthesized to provide a starting point for DNA synthesis. These primers are essential for the initiation of DNA replication.

2. **Identifying the Enzymes Involved in DNA Replication**:
- There are several key enzymes involved in DNA replication, including:
- DNA polymerases (such as DNA polymerase I and DNA polymerase III)
- Primase
- DNA ligase

3. **Analyzing the Function of Each Enzyme**:
- **Primase**: Synthesizes the RNA primer but does not remove it.
- **DNA Ligase**: Joins Okazaki fragments on the lagging strand but does not remove RNA primers.
- **DNA Polymerase I**: Has the ability to remove RNA primers and replace them with DNA.
- **DNA Polymerase II**: Primarily involved in DNA repair and does not play a significant role in removing RNA primers.

4. **Determining the Correct Enzyme**:
- The question specifically asks for the enzyme that removes the RNA primer. Among the options provided, DNA Polymerase I is known for its function to remove RNA primers and replace them with DNA nucleotides.

5. **Conclusion**:
- Therefore, the enzyme required for removing the RNA primer during DNA replication is **DNA Polymerase I**.

### Final Answer:
**DNA Polymerase I**

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