Who suggested that diseases are caused by inborn errors of metabolism?

Options

A. Beadle & Tatum
B. Rosa Franklin
C. Hershey & Chase
D. Archibald Garrod

Answer

### Step-by-Step Solution:

1. **Understanding Inborn Errors of Metabolism**:
- Inborn errors of metabolism refer to a group of rare genetic disorders that affect how the body converts food into energy. These disorders are typically caused by defects in specific enzymes that are essential for metabolic processes.

2. **Historical Context**:
- The concept of inborn errors of metabolism was first introduced in the early 20th century. It highlights the relationship between genetic defects and metabolic diseases.

3. **Key Figure**:
- The British physician who is credited with suggesting that diseases are caused by inborn errors of metabolism is Archibald Garrod. He made significant contributions to the understanding of these disorders.

4. **Garrod's Contribution**:
- Archibald Garrod's work laid the foundation for the "one gene, one enzyme" hypothesis, which posits that each gene is responsible for the production of a specific enzyme that in turn affects metabolic pathways.

5. **Conclusion**:
- Therefore, the correct answer to the question is Archibald Garrod, who suggested that diseases are caused by inborn errors of metabolism.

### Final Answer:
The person who suggested that diseases are caused by inborn errors of metabolism is Archibald Garrod.

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