One gene-one polypeptide hypothesis was proposed by

Options

A. Linus Pauling
B. V Ingram
C. Beadle and Tautum
D. Brenner

Answer

To solve the question "One gene-one polypeptide hypothesis was proposed by," we can follow these steps:

### Step-by-Step Solution:

1. **Understand the Question**: The question is asking about the scientist who proposed the one gene-one polypeptide hypothesis. This hypothesis suggests that each gene is responsible for the synthesis of a single polypeptide.

2. **Review the Options**: The options provided are:
- A) Linus Pauling
- B) Beadle and Tatum
- C) Brenner
- D) Ingram

3. **Analyze Each Option**:
- **Linus Pauling**: Known for his work on the nature of chemical bonds, not related to the one gene-one polypeptide hypothesis.
- **Ingram**: Studied the genetic basis of sickle cell anemia but did not propose the hypothesis in question.
- **Brenner**: Discovered that sequences of three DNA bases code for amino acids, but he did not propose the one gene-one polypeptide hypothesis.
- **Beadle and Tatum**: They are credited with proposing the one gene-one polypeptide hypothesis, stating that each gene corresponds to a specific enzyme or polypeptide.

4. **Select the Correct Answer**: Based on the analysis, the correct answer is **B) Beadle and Tatum**.

5. **Conclusion**: The one gene-one polypeptide hypothesis was proposed by Beadle and Tatum, which indicates that each gene is responsible for the production of a single polypeptide chain.

### Final Answer:
The one gene-one polypeptide hypothesis was proposed by **Beadle and Tatum**.

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