What becomes established from the wobble hypothesis?

Options

A. Process of peptide chain elongation
B. Economy of the number of tRNA molecules
C. Process of peptide chain initiation
D. Process of peptide chain termination

Answer

To answer the question "What becomes established from the wobble hypothesis?", we can follow these steps:

### Step-by-Step Solution:

1. **Understanding the Wobble Hypothesis**:
- The wobble hypothesis explains how the genetic code can be read by tRNA molecules. It states that the first two bases of the codon in mRNA pair strictly with the corresponding bases in the tRNA anticodon (following Watson-Crick base pairing), while the third base can form non-standard pairings.

2. **Codons and Amino Acids**:
- There are 64 possible codons (combinations of three nucleotides) that code for 20 different amino acids. This means that many amino acids are coded by more than one codon.

3. **Role of tRNA**:
- Each amino acid has at least one tRNA molecule that carries the corresponding anticodon. However, due to the wobble hypothesis, a single tRNA can recognize multiple codons that code for the same amino acid.

4. **Economy of tRNA Molecules**:
- Because of the wobble pairing, fewer tRNA molecules are needed to translate the same number of codons. This means that the wobble hypothesis allows for a more economical use of tRNA molecules.

5. **Conclusion**:
- From the wobble hypothesis, it is established that there is an economy in the number of tRNA molecules required to translate the 64 codons into the 20 amino acids.

### Final Answer:
The correct answer is: **Economy of the number of tRNA molecules**.

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