Globozoospermia is a rare condition that affects only males. It is characterized by sperm cells having a round head and no acrosome. What would this condition lead to?

Options

A. inability of the sperms to fertilise the egg
B. inability of the male to produce enough sperms
C. formation of zygote that is haploid instead of diploid
D. formation of zygotes with a missing sex chromosome

Answer

### Step-by-Step Solution:

1. **Understanding Globozoospermia**: Globozoospermia is a rare male infertility condition characterized by sperm cells that have a round head and lack an acrosome. The acrosome is crucial for sperm to penetrate the egg during fertilization.

2. **Identifying the Consequences**: The primary consequence of having sperm cells without an acrosome is their inability to fertilize an egg. The acrosome contains enzymes that are necessary for breaking down the outer layers of the egg, allowing the sperm to enter and fertilize it.

3. **Evaluating the Options**:
- **Option A**: Inability of sperm to fertilize eggs - This is true, as the lack of acrosome means the sperm cannot penetrate the egg.
- **Option B**: Inability of male to produce sperm - This is incorrect; males with globozoospermia can produce sperm, but the sperm are non-functional.
- **Option C**: Formation of zygote that is haploid instead of diploid - This is incorrect; the zygote will still be diploid if fertilization occurs, but in this case, it does not occur.
- **Option D**: Formation of zygote with missing sex chromosome - This is also incorrect; the issue is not about the chromosomes but the inability to fertilize.

4. **Conclusion**: Based on the analysis, the correct answer is **Option A**: Inability of sperm to fertilize eggs.