hnRNA is converted to mRNA after which of the following in transcription?

Options

A. initiation
B. capping
C. splicing
D. tailing

Answer

To solve the question regarding the conversion of hnRNA to mRNA during transcription, we can break down the process step by step:

### Step-by-Step Solution:

1. **Understanding hnRNA**:
- hnRNA stands for heterogeneous nuclear RNA, which is the primary transcript synthesized from DNA during transcription. It contains both coding (exons) and non-coding (introns) sequences.

2. **Transcription Process**:
- During transcription, RNA polymerase synthesizes hnRNA from a DNA template. This process occurs in the nucleus of eukaryotic cells.

3. **Post-Transcriptional Modifications**:
- After transcription, hnRNA undergoes several modifications to become mature mRNA. These modifications include:
- **Capping**: Addition of a 5' cap to the hnRNA, which protects the RNA from degradation and assists in ribosome binding during translation.
- **Polyadenylation (Tailing)**: Addition of a poly-A tail at the 3' end of the hnRNA, which also aids in stability and export from the nucleus.
- **Splicing**: Removal of introns (non-coding regions) and joining of exons (coding regions) to form a continuous coding sequence.

4. **Final Conversion to mRNA**:
- After these modifications, the processed RNA is now referred to as mRNA (messenger RNA), which is ready for translation.

5. **Conclusion**:
- Therefore, the correct answer to the question is that hnRNA is converted to mRNA after **splicing** and **polyadenylation** (tailing).

### Answer:
hnRNA is converted to mRNA after **splicing** and **polyadenylation (tailing)**.