Suggest which among the following is NOT a function attributed to endoplasmic reticulum

Options

A. Detoxification of poisons and drugs
B. Digestion/egestion of foreign materials outside the cell
C. Manufacture of fat and lipid molecules
D. Biogenesis of membranes

Explanation

To solve the question regarding the functions attributed to the endoplasmic reticulum (ER), we will analyze each option provided and determine which one does not belong to the functions of the ER.

### Step-by-Step Solution:

1. **Understand the Functions of Endoplasmic Reticulum:**
- The endoplasmic reticulum is an essential organelle in eukaryotic cells, and it has two main types: rough ER and smooth ER. Each type has specific functions.

2. **Evaluate the Options:**
- **Detoxification of poisons and drugs:** This function is primarily associated with the smooth endoplasmic reticulum, especially in liver cells where detoxification processes occur. Thus, this is a function attributed to the ER.
- **Manufacturing of fat and lipid molecules:** The smooth endoplasmic reticulum is responsible for the synthesis of lipids and fats. Therefore, this is also a function of the ER.
- **Biogenesis of membranes:** The rough endoplasmic reticulum, which has ribosomes attached to it, is involved in synthesizing proteins that are integral to cell membranes. Hence, this is a function of the ER.
- **Digestion of foreign material outside the cell:** This function is typically associated with lysosomes, which are responsible for breaking down waste materials and cellular debris. The endoplasmic reticulum does not perform digestion of foreign materials outside the cell.

3. **Identify the Incorrect Function:**
- Among the options, the function that does not belong to the endoplasmic reticulum is the digestion of foreign material outside the cell.

4. **Conclusion:**
- The correct answer is the option that states "digestion of foreign material outside the cell" as this is NOT a function attributed to the endoplasmic reticulum.

### Final Answer:
The function that is NOT attributed to the endoplasmic reticulum is **digestion of foreign material outside the cell**.

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