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The role of DNA ligase in the constructi...

The role of DNA ligase in the construction of a recombinant DNA molecule is

A

formation of phosphodiester bond between two DNA fragments

B

formation of hydrogen bonds between sticky ends of DNA fragments

C

ligation of all purine and pyrimidine bases

D

none of the above

Text Solution

Verified by Experts

The correct Answer is:
A
DNA ligase (joining or sealing enzymes) are also called genetic gum. They join two individual fragments of double-stranded DNA by forming phosphodiester bonds between them. Thus, they help in sealing gaps in DNA fragments. Therefore, they act as a molecular glue.
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