Besides better aeration and mixing properties, what other advantages do stirred tank bioreactors have over shake flasks?

Explanation

Some of the other advantages that the stirred tank bioreactors have over shake flasks are:
1. Small volumes of culture can be taken out from the reactor for sampling or testing.
2. It has a foam breaker for regulating the foam.
3. It has a control system that regulates the temperature and pH.