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How do normal cells get transformed into...

How do normal cells get transformed into cancerous neoplastic cells? Elaborate giving three examples of inducing agent.

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Normal cells get transformed into cancerous neoplastic cells due to the effect of carcinogens.
Carcinogenic agents could be physical, chemical or biological agents that changes the normal sequence of DNA. They are:
Ionising radiations like X-rays and gamma rays
Non-ionizing radiations like UV.
Chemical carcinogens present in tobacco smoke
Cellular oncogenes (c-onc) or proto-oncogenes, when activated under certain conditions cause cancer. Viruses with oncogenes can transform normal cells to cancerous cells.
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