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The pK(a) of acteylsalicylic acid (aspir...

The `pK_(a)` of acteylsalicylic acid (aspirin) is `3.5`. The pH of gastric juice in human stomach is about `2-3` and the pH in the small intestine is about 8. Aspirin will be:

A

Unionized in the small intestine and in the stomach

B

Completely ionized in the small intestine and in the stomach

C

Ionized in the stomach and almost unionized in the small intestine

D

Ionized in the small intestine and almost unionized in the stomach

Text Solution

Verified by Experts

The correct Answer is:
D
Aspirin is a weak acid. Due to common ion effect it is unionised in acid medium but completely ionised in alkaline medium.
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