Which of the following statements is not correct

Options

A. Lysosomes are formed by the process of packaging in the endoplasmic reticulum
B. Lysosomes have numerous hydrolytic enzymes
C. The hydrolytic enzymes of lysosomes are active under acidic pH
D. Lysosomes are membrane bound structures

Explanation

To determine which statement about lysosomes is not correct, we will analyze each provided statement step by step.

### Step-by-Step Solution:

1. **Statement Analysis**:
- **Statement A**: "Lysosomes are formed by the process of packaging in endoplasmic reticulum."
- **Statement B**: "Lysosomes have numerous hydrolytic enzymes."
- **Statement C**: "The hydrolytic enzymes of lysosomes are active under acidic pH."
- **Statement D**: "Lysosomes are membrane-bound structures."

2. **Evaluating Statement A**:
- Lysosomes are not formed in the endoplasmic reticulum. Instead, they are formed by the Golgi apparatus (Golgi bodies). Therefore, this statement is incorrect.

3. **Evaluating Statement B**:
- It is a well-known fact that lysosomes contain numerous hydrolytic enzymes that help in the digestion of macromolecules. This statement is correct.

4. **Evaluating Statement C**:
- Hydrolytic enzymes in lysosomes are indeed active under acidic pH, which is essential for their function. This statement is also correct.

5. **Evaluating Statement D**:
- Lysosomes are indeed membrane-bound organelles, which is a defining characteristic of these structures. This statement is correct.

6. **Conclusion**:
- Based on the evaluations, the only incorrect statement is **Statement A**. Therefore, the answer to the question is that "Lysosomes are formed by the process of packaging in endoplasmic reticulum" is the statement that is not correct.

### Final Answer:
**Statement A is not correct.**

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