In Myasthenia gravis acetylcholine

Options

A. Receptors on motor end plate are reduced
B. Secretion from nerve terminals is reduced
C. Esterase activity is inhibited
D. Secretion from nerve terminals is enhanced

Answer

A

Explanation

Nerves communicate with muscles by releasing neurotransmitters that fit precisely into receptor sites on the muscle cells at the nerve – muscular junction.
In myasthenia gravis, our immune system produces antibodies that block or destroy many of our receptor sites for a neurotransmitter called acetylcholine. With fever receptor sites available our muscles receive fever nerve signals, resulting in weakness.