To explain the mechanism of enzymatic action, who proposed ''Lock and key hypothesis''

Options

A. Fischer
B. Jacob
C. Koshland
D. Sumner

Answer

A

Explanation

Lock and the key hypothesis were suggested by Emil Fischer in 1894. The enzyme molecule operates by chemically uniting with substrate molecules. The combination of two is known as an enzyme-substrate complex. An enzyme may combine two small substrate molecules into one larger product molecule or may split a large substrate molecule into two smaller product molecules.