Pyruvic acid is converted into a compound before formation of oxaloacetic acid in the citric acid cycle, this compound is
Or
Which of the following metabolites enter the TCA cycle during glucose oxidation.

Options

A. Acetyl CoA
B. Acetoacetic acid
C. Lactic acid
D. cis aconitic acid

Answer

A

Explanation

Pyruvate which is formed by the glycolytic metabolism of carbohydrates in the cytosol after it enters the mitochondrial matrix undergoes oxidative decarboxylation by a complex set of reactions catalyzed by pyruvate dehydrogenase. It requires several coenzymes like `NAD^(+)` and coenzyme A.
Pyruvic acid `+COA +NAD^(+) underset("Pyruvate dehydroganate")rarr ` 2 Acetyl `COA +CO_(2) +NADH +H^(+)`