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Which of the following metabolities ente...

Which of the following metabolities enter the TCA cycle during glucose oxidation ?

A

Acetyl CoA

B

Acetoacetic acid

C

Lactic acid

D

cis aconitic acid

Text Solution

Verified by Experts

The correct Answer is:
A
Pyruvate which is formed by the glycolytic metabolism of carbohydrates in the cytosol after it enters the mitochondrial matrix undergoes oxidative decarboxylation by a complex set of reactions catalyzed by pyruvate dehydrogenase. It requires several coenzymes like `NAD^(+)` and coenzyme A.
Pyruvic acid `+COA +NAD^(+) underset("Pyruvate dehydroganate")rarr ` 2 Acetyl `COA +CO_(2) +NADH +H^(+)`
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