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All enzymes of TCA cycle are located in ...

All enzymes of TCA cycle are located in the mitochondrial matrix except one which is located in inner mitochondrial membranes in eukaryoes and in cytosol in prokaryotes. This enzyme is

A

Lactate dehydrogenase

B

Isocitrate Dehydrogenase

C

Malate dehydrogenase

D

Succinate dehydrogenase

Text Solution

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The correct Answer is:
D
Succinate dehydrogenase is attached to the inner mitochondrial member. All other enzymes of the Krebs cycle are located within the metric of mitochondria. The reason behind this does in the properties of `FAD^(+)` unlike `NAD^(+) , FAD^(+)` is not free to different within the mitochondrion, it is an integral part of the inner mitochondrial membrane its reduced from `FADH_2` contributes electrons directly to electron transport chain.
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