The enzyme mediating the reaction of Kreb's cycle during cellular respiration in animal found in

Options

A. Cytoplasm
B. Ribosome
C. Lysosome
D. Mitochondria

Explanation

### Step-by-Step Solution:

1. **Understanding the Kreb's Cycle**: The Kreb's cycle, also known as the citric acid cycle or the tricarboxylic acid (TCA) cycle, is a crucial part of cellular respiration. It takes place in the mitochondria of cells and is responsible for generating energy through the oxidation of acetyl-CoA.

2. **Identifying the Location**: The question asks where the enzymes that mediate the reactions of the Kreb's cycle are found in animal cells. The options provided are Cytoplasm, Ribosome, Lysosome, and Mitochondria.

3. **Analyzing Each Option**:
- **Cytoplasm**: This is the fluid that fills the cell and contains various organelles, but it is not where the Kreb's cycle occurs.
- **Ribosome**: Ribosomes are the sites of protein synthesis and do not mediate the Kreb's cycle.
- **Lysosome**: Lysosomes contain digestive enzymes for breaking down waste materials and are not involved in the Kreb's cycle.
- **Mitochondria**: Mitochondria are known as the powerhouse of the cell and are specifically where the Kreb's cycle takes place.

4. **Conclusion**: Based on the analysis, the enzymes mediating the reactions of the Kreb's cycle during cellular respiration in animals are found in the mitochondria.

### Final Answer:
The enzymes mediating the reaction of Kreb's cycle during cellular respiration in animals are found in the **Mitochondria**.

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