Microtubule depolymerizing durg such as colchicine is expected to

Options

A. Inhibit spindle formation during mitosis
B. Inhibit cytokinesis
C. Allow mitosis beyond metaphase
D. Induce formation of multiple contractile rings

Answer

A

Explanation

Colchicine is a potent inhibitor to progress cell cycle from metaphase to anaphase. Thus it allows the inhibition of spindle formation which prevents coiling of chromosome towards the opposite pole.