Osteoporosis, an age-related disease of skeletal system, may occur due to :

Options

A. Immune disorder affecting neuromuscular junction leading to fatigue
B. High concentration of `Ca^(2+) and Na^(+)`
C. Decreased level of oestrogen
D. Accumulation of uric acid leading to inflammation of joints

Answer

C

Explanation

Osteoporosis is a reduction in bone mineral density, resulting in bones that are brittle and liable to fracture. Infection, injury and synovitis can cause localised osteoporosis of adjacent bone. Generalised osteoporosis is common in elderly and in women after menopause.