Conn’s disease is caused by the over-secretion of

Options

A. ADH
B. ACTH
C. Aldosterone
D. Oxytocin

Explanation

**Step-by-Step Solution:**

1. **Understanding Conn's Disease**: Conn's disease, also known as primary hyperaldosteronism, is a condition characterized by the overproduction of a specific hormone.

2. **Identifying the Hormone**: The hormone that is over-secreted in Conn's disease is aldosterone. Aldosterone is produced by the adrenal glands, specifically in the zona glomerulosa of the adrenal cortex.

3. **Function of Aldosterone**: Aldosterone plays a crucial role in regulating sodium and potassium levels in the body. It promotes sodium reabsorption and potassium excretion in the kidneys, which helps to control blood pressure and maintain electrolyte balance.

4. **Causes of Over-Secretion**: The over-secretion of aldosterone in Conn's disease is often due to a small tumor in the adrenal gland, known as an adrenal adenoma. This tumor causes the adrenal gland to produce excess aldosterone.

5. **Conclusion**: Therefore, Conn's disease is caused by the over-secretion of aldosterone.

**Final Answer**: Conn's disease is caused by the over-secretion of aldosterone.

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