Addison's disease is characterised by

Options

A. Elongation of limb bones and jaw becomes broad
B. Hypertension and enlargement of thyroid
C. Loss of appetite, vomiting, muscular weakness, lowering of BMR, blood pressure and bronze coloured patches of skin
D. Obesity, osteoporosis and glycosuria

Explanation

### Step-by-Step Solution:

1. **Understanding Addison's Disease**:
- Addison's disease is a disorder that occurs when the adrenal glands do not produce enough hormones, particularly cortisol and aldosterone. This condition is also known as adrenal insufficiency.

2. **Symptoms of Addison's Disease**:
- The disease is characterized by several key symptoms:
- **Loss of Appetite**: Individuals may experience a decreased desire to eat.
- **Vomiting**: Nausea and vomiting are common symptoms.
- **Muscular Weakness**: Patients often feel weak and fatigued.
- **Lowering of Basal Metabolic Rate (BMR)**: There is a decrease in the body's metabolic rate.
- **Blood Pressure Changes**: Patients may experience fluctuations in blood pressure, often leading to hypotension (low blood pressure).
- **Bronze-Colored Patches of Skin**: A distinctive symptom of Addison's disease is hyperpigmentation, which results in bronze or dark patches on the skin.

3. **Conclusion**:
- In summary, Addison's disease is characterized by a combination of symptoms including loss of appetite, vomiting, muscular weakness, low BMR, blood pressure fluctuations, and bronze-colored skin patches.

### Final Answer:
Addison's disease is characterized by loss of appetite, vomiting, muscular weakness, lowering of basal metabolic rate, blood pressure fluctuations, and bronze-colored patches of skin.

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