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The method developed by Matthew Mesels...

The method developed by Matthew Meselson and Franklin Stahl to separate heavy DNA with` ^(15)`N from DNA with `^(14)` N, for providing evidence for semi- conservative replication of DNA is

A

Ion exchange chromatography

B

Density gradient centrifugation

C

Buoyant density centrifugation

D

Gel filtration

Text Solution

Verified by Experts

The correct Answer is:
B
Semi conservative replication by Meselson and Stahl in 1958 using CsCl density gradient centrifugation to separate DNA with Different densities.
The principle of this method is that each large molecule like nucleic acid or protein attains its specific buoyant density when such a solution is subjected to centrifugal force.
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