Who proposed the 'Signal hyothesis' meant for the biosynthesis of secretory type of proteins

Options

A. Baltimore
B. Camillio Golgi
C. Blobel and Sabatini
D. Sheeler and Bianchi

Answer

C

Explanation

In 1971 Gunter Blobel and David Sabatini identified that for the cytoplasmically synthesised proteins targeted to E.R. use a signal sequence to direct them to ER membrane.