What is the first step in the Southern Blot technique

Options

A. Denaturation of DNA on the gel for hybridization with specific probe
B. Production of a group of genetically identical cells
C. Digestion of DNA by restriction enzyme
D. Denaturation of DNA from a nucleated cell such as the one from the scene of crime

Answer

C

Explanation

Steps Involves in southern blotting are as followers.