Identify the correct statement

Options

A. RNA polymerase binds with Rho factor to terminate the process of transcription in bacteria
B. The coding strand in a transcription unit is copied to an mRNA
C. Split gene arrangement is characteristic of prokaryotes
D. In capping, methyl guanosine triphosphate is added to the 3' end of hnRNA

Explanation

**Step-by-Step Solution:**

1. **Understanding the Question**: The question asks to identify the correct statement regarding molecular biology, particularly focusing on transcription and gene structure.

2. **Analyzing Option 1**:
- The statement claims that "RNA polymerase points with root factor to terminate the process of transcription in bacteria."
- This statement is correct. In bacteria, RNA polymerase, along with a sigma factor, initiates transcription, and a rho factor is indeed involved in terminating the transcription process.

3. **Analyzing Option 2**:
- The statement mentions that "the coding strand in a transcription unit is copied to an mRNA."
- This statement is misleading. The mRNA is synthesized from the template strand, which is complementary to the coding strand. The coding strand is not directly copied; rather, the mRNA sequence resembles the coding strand, with uracil replacing thymine. Therefore, this statement is incorrect.

4. **Analyzing Option 3**:
- The statement claims that "split gene arrangement is characteristic of prokaryotes."
- This is incorrect. Split genes, which contain introns and exons, are characteristic of eukaryotes. Prokaryotes do not have introns; they only have exons.

5. **Analyzing Option 4**:
- The statement refers to "methyl guanosine triphosphate applied to the 3 prime end of HnRNA."
- This is incorrect. The methyl guanosine cap is added to the 5' end of the mRNA, not the 3' end. The 3' end typically receives a poly-A tail.

6. **Conclusion**: After analyzing all options, the only correct statement is option 1. Therefore, the correct answer is option 1.