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The defect sickle-cell anaemia is caused...

The defect sickle-cell anaemia is caused by the `"_____"` of glutamic acid by the valine at the `6^(th)` position of the `"_____"` globin chain of the haemoglobin molecule.

A

Substitution, `beta`

B

Deletion, `alpha`

C

Duplication, `beta`

D

Translocation , `alpha`

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The correct Answer is:
A
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The defect sickle - cell anaemia is caused by the ________ of glutamic acid by valine at the 6th position of the ________ globin chain of the haemoglobin molecule.

Assertion :-Sickle-cell anaemia is caused by the substitutin of glutamic acid by valine at the sixth position of the beat globin chain of the hemoglobin moecule. Reason :- It is due to the single base substatution at the sixth codon of the beta lobin gene from GUG to GAG.

Sickle cell anaemia is caused by the subsitution of :

What causes sickle cell anaemia?

Sickle cell anaemia is caused by the substitution of Glu by ………... at the sixth position of the beta-globin chain of the hemoglobin molecule.

Sickle-cell anaemia is caused due to the substitution of :

" Identify the codon that codes for the amino acid at sixth position of beta globin chain of normal haemoglobin molecule "

Read the following statement s and choose the correct option In p[henylketonuria the affected person does not secrete the enzyme to con vert pheylalnine to typrosine (II)Possibility of male becoming haemophiliac is extremely rare (III) Sickle cell anaemia is caused by the substitution of glutamic acid by valine at fifth position of beta chain of haemoglobin (IV) Myotonic dystrophy is an autosomla dominant trait

AAKASH INSTITUTE-PRINCIPLES OF INHERITANCE AND VARIATION-Assignment (SECTION-B) Objective Type Questions
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  2. Mark the correct statement (w.r.t. sickle cell -anaemia)

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  3. The defect sickle-cell anaemia is caused by the "" of glutamic acid by...

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  4. A Y-linked gene is responsible for hypertrichosis (long pair hair on e...

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  5. A normal woman, whose father had color blindness, married a normal man...

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  6. Mr. steven is suffering from haemophilia and cystic fibrosis . His fat...

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  7. Select incorrect one (w.r.t reciprocal cross)

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  8. The chromosome maps are not accurate maps because

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  9. In Lathyrus odoratus, hybrid blue flowered and long pollen plant is te...

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  10. Find out the frequency of AabbCcDdee if parents are AabbCCddEe and Aab...

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  11. In complete dominance

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  12. Progeny with blood group 'O' can be obtained cross

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  13. If a agouti mice (CcAa) is crossed with albino mice (ccAA), then how m...

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  14. Match the following - (w.r.t. Pedigree analysis )

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  15. Which of the following parental combination has produced mutant offs...

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  16. Epistasis and dominance are respectively

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  17. Which of the following combination seems to have some linkage in chara...

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  18. A diploid organism is heterozygous for five loci and homozygous for 2 ...

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  19. Lesch Nyhan disease is an X-linked recessive disorder that causes neur...

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  20. How many types of zygotic combinations are possible between a cross Aa...

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