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In sickle-cell anaemia substitution of g...

In sickle-cell anaemia substitution of glutamic acid molecule by valine molecule takes place at

A

Position 6 of the a-chain of haemoglobin

B

Position 6 of the B- chain of haemoglobin

C

Position 5 of the B-chain of haemoglobin

D

Position 5 of the a-chain of haemoglobin

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Verified by Experts

The correct Answer is:
B
Sickle, cell anaemia is an example of point mutation in the B-haemoglobin gene that converts GAG codon to GUG at the position 6 of B-chain. This codes amino acid valine in place of glutamic acid
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ARIHANT NEET-HUMAN GENETICS-Chapter Exercise (c) Medical entrances gallery (Collection of questions asked in NEET & Various Medical Entrance Exams)
  1. An abnormal human baby with XXX sex chromosomes was born due to

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  2. Which of the following is correct?

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  3. In sickle-cell anaemia substitution of glutamic acid molecule by valin...

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  4. If a boy's father has haemophilia and mither is heterozygous what is t...

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  5. A human female with turner's syndrome

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  6. A man whose father was colourblind marries a woman, who had a colourbl...

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  7. A couple both carriers of sickle cell anaemia planning to get married,...

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  8. Which of the following is correctly matched?

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  9. A person affected with phenylketonuria lacks an enzyme that converts t...

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  10. In sickle cell anaemia, the sequence of amino acid from first to seven...

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  11. Anish is having colour blindness and married to Sheela, who is not col...

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  12. The genotype of a person suffering from Klinefelter's symdrome is

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  13. In alpha thalasssemia the gene HBAI is located on chromosome

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  14. Sickle-cell anaemia is caused due to the substitution of :

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  15. Down's syndrome is an example

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  16. In down's syndrome (Mongolism), each cell has how many chromosomes?

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  17. In the given pedigree, the shaded individuals are homozygous recessive...

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  18. Haemophilia is related to

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  19. The gene of sickle cell anaemia is inherited by

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  20. Represented below is the inheritance pattern of a certain type of trai...

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