Thalassemia and sickle cell anemia are caused due to a problem in globin molecule synthesis. Select the correct statement

Options

A. Both are due to a qualitative defect in globin chain synthesis
B. Both are due to a qualitative defect in globin chain synthesis.
C. Thalassemia is due to less synthesis of globin molecules.
D. Sickle cell anemia is due to a quantitative problem of globin molecules

Explanation

Thalassemia differs from sickle-cell anaemia in that the former is a quantitative problem of synthesising too few globin molecules while the latter is a qualitative problem of synthesising an incorrectly functioning globin.