Anaphase promoting complex (APC) is a pr...

Anaphase promoting complex (APC) is a protein degradation machinery necessary for proper mitosis of animal cells. If APC is defective in a human cell, which of the following is expected to occur

Chromosomes will not condense

Chromosomes wiil be fragmented

Chromosomes will not segregate

Recombination of chromosome arms will occur

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The correct Answer is:

If anaphase promoting complex is defective in a human cell, the chromosomes will not segregate during anaphase of mitosis. APC triggers the transition from metaphase to anaphase by tagging specific proteins for degradation.
Concept Enhancer Anaphase stage of meiosis is characterised by two events
(a) Splitting of centromeres and segregation of chromosormes.
(b) Movement of chromatids towards the opposite poles.

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