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Select the correct combination of statem...

Select the correct combination of statements regarding Myasthenia gravis
I. It is an auto immune disorder.
II. It causes in sufficient ecetylcholine binding that effects muscular contraction.
III. Antibodies are developed against acetylcholine.
IV. Antibodies are developed against acetylcholine receptors
V. It causes drooping of eyelids.

A

I,II,IV,VI

B

I,III,V,II

C

I,II,IV,VI

D

II,III,IV,V

Text Solution

Verified by Experts

The correct Answer is:
C
Statements I, II, IV and VI are correct.
Myasthemia gravis is an auto immune neuromuscular disease that is cogenítal. It Ieads to muscle weakness, It ia caused by circulating antibodies that block acetylcholine receptors at the post-synaptic neuromuscular junction inhibiting the excitatory effects of acetylcholine and nicotic receptors at neuromuscular junctions. First noticeable symptom is weakening of eye muscle leading to drooping of eyelids.
It is treated medically with acetylcholine esterase inhibitors or immuno suppressants.
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