Which of the following hormones can play a significant role in osteoporesis

Options

A. Estrogen and parathyroid hormone
B. Progesterone and aldosteron
C. Aldosterone and prolactin
D. Parathyroid hormone and prolactin

Answer

A

Explanation

Estrogen and parathyroid hormone can play significant role in osteoporosis. It is caused due to the deficiency of estrogen and oxcessive activity of parathormones. Estrogen helps to promote die activity of osteoblast (helps in the formation of bone cells) and inhibits osteoclast (destruct the bones). On the other hand, parathomone promotes the mobilisation ol calcium from bones into blood hence causes demineralisation.
The other listed hormones also contribute to osteoporosis but their effects aro insignificant or very less. e.g., low level of progesterone and aldosterone causes bone loss whereas raised level of prolactin have been linked with osteoporosis.