OXYMERCURATION-DEMERCURATION MECHANISM

OXYMERCURATION-DEMERCURATION METHOD:

Preparation OF Alcohol and Ether by Acidic Hydration || Oxymercuration Demercuration reaction || Hydroboration oxidation || Reaction OF R-X with HOH and NaOH ( by SN-Reaction )

Oxymercuration demercuration reacti on is process of addition H_2O according to Markownikoff's rule without any rearrangement . CH_3 - CH = CH_2 underset(NaBH_4. overset(odot)OH)overset(Hg(OAc)_2 . H_2O) to CH_3 - underset(OH)underset(|)CH=CH_3 Mechanism : Hg(OAc)_2 iffoverset(oplus)Hg(OAc) + Acoverset(odot)O Base overset(Ɵ)OH is used to neutralise H^(oplus) produced during the reaction :

Oxymercuration demercuration reacti on is process of addition H_2O according to Markownikoff's rule without any rearrangement . CH_3 - CH = CH_2 underset(NaBH_4. overset(odot)OH)overset(Hg(OAc)_2 . H_2O) to CH_3 - underset(OH)underset(|)CH=CH_3 Mechanism : Hg(OAc)_2 iffoverset(oplus)Hg(OAc) + Acoverset(odot)O Base overset(Ɵ)OH is used to neutralise H^(oplus) produced during the reaction :

Oxymercuration demercuration reacti on is process of addition H_2O according to Markownikoff's rule without any rearrangement . CH_3 - CH = CH_2 underset(NaBH_4. overset(odot)OH)overset(Hg(OAc)_2 . H_2O) to CH_3 - underset(OH)underset(|)CH=CH_3 Mechanism : Hg(OAc)_2 iffoverset(oplus)Hg(OAc) + Acoverset(odot)O Base overset(Ɵ)OH is used to neutralise H^(oplus) produced during the reaction : Major product :

Oxymercuration demercuration reacti on is process of addition H_2O according to Markownikoff's rule without any rearrangement . CH_3 - CH = CH_2 underset(NaBH_4. overset(odot)OH)overset(Hg(OAc)_2 . H_2O) to CH_3 - underset(OH)underset(|)CH=CH_3 Mechanism : Hg(OAc)_2 iffoverset(oplus)Hg(OAc) + Acoverset(odot)O Base overset(Ɵ)OH is used to neutralise H^(oplus) produced during the reaction : Major product :

Oxymercuration-Demercuration (OMDM) reaction

Method OF Preparation OF Alcohol by Acidic Hydration OF Alkene || OMDM (Oxymercuration and Demercuration) OF Alkenes || Kucherov Reaction

Addition of mercuric acetate in the presence of water is called as oxymercuration.The adduct obtained gives alcohol on reduction with NaBH_4 in alkaline medium.This is known as demercuration.Oxymercuration demercuration allows Markownikoff's addition of H, OH without rearrangement.The net result is the addition of H_2O Answer the following question : CH_3-undersetunderset(CH_3)(|)oversetoverset(CH_3)(|)(C)-CH=CH_2underset((ii)CH_3OH NaBH_4NaOH)overset((i)Hg(OAc)_2.THF)toAoverset(HI(Conc.))toB Product B is :