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Order Of Reactivity Of Acid Derivative W...

Order Of Reactivity Of Acid Derivative With Nucleophile

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Which of the following orders regarding the base strength of a leaving group in a reaction of an acid derivative with a nucleophile is correct :

Correct order of reactivity of following acid derivatives is : MeCOCI MeCON_(3) MeCOOCOMe MECOOMe

The reactivity of acid derivatives in general follows the order : The above order of reactivity can be explained in terms of the : (i) Basicity of leaving group (ii) Resonance effect (iii) Inductive effect Weaker is the basic character of leaving group, more is the reactivity of acid derivative. In general, all the acid derivatives show resonance as follows: More is the stablization, lesser is the reactivity and vice-versa. Which among the following ester is most reactive towards nucleophilic attack ?

Aryl halides are extermely less reactive towards nucleophilic substitution. Predictand explain the order of reactivity of the compounds towards nucleophilic substitution.

The reactivity of acid derivatives in general follows the order: The above order of reactivity can be explained in terms of the: (i) Basicity of leaving group (ii) Resonance effect (iii) Inductive effect Weaker is the basic character of leaving group, more is the reactivity of acid derivative. In general, all the acid derivatives show resonance as follows: More is the stabilization, lesser is the reactivity and vice -versa. Which among the following acid halides is the most reactive?