Gabriel Phthalimide Synthesis

Consider the following conversion : Amongst the following, how many methods can be used in any one of steps involved in the mentioned conversion? i. Hoffmann bromamide degradation ii. Gabriel phthalimide synthesis iii. Sandmeyer reaction iv. Clemmensen reduction v. Mendius reduction

(a) Account for the following : (i) Direct nitration of aniline yields significant amount of meta derivative. (ii) Primary aromatic cannot be prepared by Gabriel phthalimide synthesis. (b) Carry out the following conversions : (i) Ethanoic acid into methanamine. (ii) Aniline to p-Bromoniline. (c) Arrange the following in increasing order of basic strength : Aniline, p-nitroaniline and p-toludine.

Account for the following: (i) pK_(b) of aniline is more than that of methylamine. (ii) Ethylamine is soluble in water whereas aniline is not. (iii) Methylamine in water reacts with ferric chloride to precipitate hydrated ferric oxide. (iv) Although amino group is o– and p– directing in aromatic electrophilic substitution reactions, aniline on nitration gives a substantial amount of m-nitroaniline. (v) Aniline does not undergo Friedel-Crafts reaction. (vi) Diazonium salts of aromatic amines are more stable than those of aliphatic amines. (vii) Gabriel phthalimide synthesis is preferred for synthesising primary amines.

Which of the following may be prepared by Galbriel phthalimide synthesis?

Which can not formed by Gabriel phthalamide synthesis

Preparation OF Amine by (1) from Nitrile ,Isonitrile(2)Amides(3)Nitro Compounds || Gabriel's Phthalimide Systhesis OF Amine