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The structure of AZT (azidothymine) is g...

The structure of `AZT` (azidothymine) is given below. It is used to treat `AIDS` patients. If fights and `AIDS` infection but does not cure it.

Which of the following statements are correct about `AZT` ?

A

It shows acidic property.

B

It undergoes tautomerisation.

C

It gives white precipitate with `(ZnCl_2 + HCl)` (Lucas reagent).

D

Azide ion `(N_3^(Ө))` cannot replace `Br^(Ө))` by `SN^2` reaction.

Text Solution

Verified by Experts

The correct Answer is:
A, B, D

For `(a), H` atom attached to `N` is acidic due to the presence of the two electron-withdrawing `(C=O)` groups. Its ion is resonance stabilised.

`( c) 1^@ ROH` does not give Lucas test at room temperature.
`(d)` Strong `(C-N)` bond is not broken by `Br^(Ө)`.
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  9. Which of the following statement (s) is //are correct about the prepa...

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  14. underset((A))(PhCOOH) overset((i) N2 H,H^(oplus)) underset((ii) Delta)...

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  15. underset((A))(EtCOCl) overset((i)H2 N.OH) underset ((ii) overset(Ө)O H...

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  16. underset((A))(MeCH(2)COOH)underset(underset((iii)Ag(2)O //Pt)((ii)CH(2...

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  17. and find which of the following statements are correct.

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  18. The structure of AZT (azidothymine) is given below. It is used to trea...

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  19. above and find which of the following functional groups are present in...

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  20. and find the product (s) of the controlled hydrolysis of AZT.

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