Assertion (A) : Non-competitive inhibitor inhibits the catalytic activity of enzyme by binding with its active site.
Reason (R): Non-competitive inhibitor changes the shape of the active site in such a way that substrate can't recognise it

Options

A. (A) and (R ) both are correct statement but reason does not explain (A)
B. (A) and (R ) both are correct statements and (R ) explains the (A)
C. Both (A) and (R ) are wrong statement
D. (A) is wrong statement and (R ) is correct statement

Answer

D

Explanation

Non-competitive inhibitor inhibits the catalytic activity of enzyme by binding with its allosteric site.