Whate would be the corrcct base sequence in mRNA for the given DNA strand 5' -AAATGCCTTAAGC- 3'

Options

A. `5'- GCUUAAGGCAUU -3'`
B. `5'-UUACGGAATTCG-3'`
C. `3'-UUACGGAAUUCG -5'`
D. `3 '- AAUGCCUUAUCG -5'`

Answer

To determine the correct base sequence in mRNA for the given DNA strand, we will follow these steps:

### Step-by-Step Solution:

1. **Identify the DNA Strand**: The given DNA strand is 5' - AAATGCCTTAAGC - 3'.

2. **Understand the Base Pairing Rules**: In DNA, the base pairing rules are:
- Adenine (A) pairs with Thymine (T)
- Cytosine (C) pairs with Guanine (G)

However, in RNA, Thymine (T) is replaced by Uracil (U). Therefore, the base pairing rules for RNA transcription are:
- Adenine (A) pairs with Uracil (U)
- Cytosine (C) pairs with Guanine (G)
- Guanine (G) pairs with Cytosine (C)
- Thymine (T) pairs with Adenine (A)

3. **Transcribe the DNA to mRNA**: We will transcribe the DNA sequence into mRNA by replacing each base according to the rules mentioned above.
- The DNA sequence is read from 5' to 3', and we will create the mRNA sequence in the 5' to 3' direction as well.

- **Transcription**:
- A (from DNA) → U (in mRNA)
- A (from DNA) → U (in mRNA)
- A (from DNA) → U (in mRNA)
- T (from DNA) → A (in mRNA)
- G (from DNA) → C (in mRNA)
- C (from DNA) → G (in mRNA)
- C (from DNA) → G (in mRNA)
- T (from DNA) → A (in mRNA)
- T (from DNA) → A (in mRNA)
- A (from DNA) → U (in mRNA)
- G (from DNA) → C (in mRNA)
- C (from DNA) → G (in mRNA)

4. **Write the mRNA Sequence**: After applying the base pairing rules, the mRNA sequence corresponding to the given DNA strand is:
- 5' - U U U A C G G A A U U C G - 3'

5. **Final Answer**: The correct base sequence in mRNA for the given DNA strand is:
- **5' - U U U A C G G A A U U C G - 3'**