Which antibiotic inhibits interaction between t-RNA and m-RNA during bacterial protein synthesis ?

Options

A. Neomycin
B. Tetracycline
C. Streptomycin
D. Erythromycin

Answer

**Step-by-Step Solution:**

1. **Understanding the Question**: The question asks which antibiotic inhibits the interaction between tRNA (transfer RNA) and mRNA (messenger RNA) during bacterial protein synthesis.

2. **Identifying the Key Components**: In bacterial protein synthesis, tRNA brings amino acids to the ribosome, where mRNA provides the template for the sequence of amino acids to be assembled into a protein. The ribosome is composed of two subunits: the smaller 30S subunit and the larger 50S subunit.

3. **Listing the Antibiotics**: The antibiotics mentioned in the question are Neomycin, Tetracycline, Streptomycin, and Erythromycin. Each of these antibiotics has a different mechanism of action.

4. **Analyzing Each Antibiotic**:
- **Neomycin**: This antibiotic interferes with the functioning of the ribosome but does not specifically inhibit the interaction between tRNA and mRNA.
- **Tetracycline**: This antibiotic binds to the tRNA, preventing it from delivering amino acids to the ribosome, thereby inhibiting the interaction between tRNA and mRNA.
- **Streptomycin**: This antibiotic binds to the 30S ribosomal subunit but does not directly affect the tRNA and mRNA interaction.
- **Erythromycin**: This antibiotic binds to the 50S ribosomal subunit, also not directly affecting the tRNA and mRNA interaction.

5. **Conclusion**: Based on the analysis, Tetracycline is the antibiotic that inhibits the interaction between tRNA and mRNA during bacterial protein synthesis.

**Final Answer**: Tetracycline.

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