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The distance between the genes a,b,c and...

The distance between the genes a,b,c and d in mapping units are a-d=3.5 , b-c=1,a-b=6,c-d=1.5,a-c=5 Find out the sequence of arrangement of these genes:

A

acdb

B

abcd

C

acbd

D

adcb

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To determine the sequence of arrangement of the genes A, B, C, and D based on the given distances in mapping units, we can follow these steps: ### Step-by-Step Solution: 1. **List the Distances**: - a-d = 3.5 - b-c = 1 - a-b = 6 - c-d = 1.5 - a-c = 5 2. **Start with Gene A**: - Assume gene A is at position 0 on a linear chromosome. 3. **Position Gene B**: - Since the distance between A and B is 6, place gene B at position 6 (A at 0, B at 6). 4. **Position Gene C**: - The distance between A and C is 5, so place gene C at position 5 (A at 0, C at 5). 5. **Position Gene D**: - The distance between A and D is 3.5, so place gene D at position 3.5 (A at 0, D at 3.5). 6. **Check Distances**: - Now we need to check the distances between the other genes: - Distance between B and C: B (6) - C (5) = 1 (correct) - Distance between C and D: C (5) - D (3.5) = 1.5 (correct) - Distance between A and D: A (0) - D (3.5) = 3.5 (correct) - Distance between A and B: A (0) - B (6) = 6 (correct) - Distance between A and C: A (0) - C (5) = 5 (correct) 7. **Final Arrangement**: - The arrangement based on the positions is: A - D - C - B. ### Conclusion: The sequence of arrangement of the genes is **A, D, C, B**.
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GRB PUBLICATION-CHROMOSOMAL BASIS OF INHERITANCE-Chromosome mapping
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