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What are transgenic animals? How are the...

What are transgenic animals? How are they obtained? Add a note on their significance.

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An animal developed by introducing the desired foreign gene is called a Transgenic animal. Transgenic animals can be produced by the following methods.
1. Microinjection of desired genes into pronucleus of the fertilized egg.
2. Retroviral infection of fertilised eggs at 4 to 8 celled stages.
3. Genetic alterations of embryonic stem cells [ESC] and their reintroduction into the blastocyst. Transgenic animals are useful in biological, biomedical and biotechnological researches especially in animal husbandary, dairy and pharmaceutical industries.
Note : Transgenic animals are used as bioreactors for mass production of drugs and proteins. It is called genefarming or molecular farming.
e.g. :
Organism Table .

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