Which of the following is not derived from cholesterol?

Options

A. Vitamin-D
B. Bile juice
C. Insulin
D. Sex hormone

Answer

To determine which of the following options is not derived from cholesterol, we need to analyze each option provided:

1. **Vitamin D**: Cholesterol is a precursor for the synthesis of Vitamin D in the skin when exposed to sunlight. Therefore, Vitamin D is derived from cholesterol.

2. **Bile Juice**: Bile acids, which are a component of bile juice, are synthesized from cholesterol. Thus, bile juice is derived from cholesterol.

3. **Insulin**: Insulin is a peptide hormone produced by the pancreas and is not derived from cholesterol. It is synthesized from amino acids, not cholesterol.

4. **Sex Hormones**: Sex hormones, such as estrogen and testosterone, are synthesized from cholesterol. Therefore, sex hormones are derived from cholesterol.

After analyzing all the options, we conclude that the correct answer is:

**Insulin** is not derived from cholesterol.

### Step-by-Step Solution:
1. Identify the options given in the question.
2. Analyze each option to determine if it is derived from cholesterol.
3. Conclude which option is not derived from cholesterol.